She is not named in the Bible, but Isaiah's wife is referred to as a prophetess. Some sources say the reason for her designation as a prophetess is that she possessed the gift of prophecy like Deborah, Huldah, and others, and others say it is because she was a prophet's wife.

Her husband, Isaiah, lived circa 765 B.C., and served as a prophet during the reigns of Jotham, Ahaz, and Hezekiah, the successors of Uzziah, king of Judah. Isaiah foretold the birth of Jesus (Isaiah 7:14), one of the most important prophecies from the Old Testament to be fulfilled and written about in the New Testament. Shortly after that reference in Chapter 7, Isaiah refers to his wife as “the prophetess.”

A rough translation of the Lord's name for the child of the prophetess and Isaiah means “quick defeat and access to the spoils of war.” The child's name foretold a time when Judah would overpower and defeat her enemies. Damascus at that time was the capital of Aramaea, and Samaria was the capital of Israel. There are no other mentions of the prophetess wife of Isaiah following that reference.