If William Shakespeare left Anne for London when he was twenty-three, she would have been thirty-one. Susanna, their first child, would have been five, the twins, Judith and Hamnet, only two. We know nothing about the affection William and Anne had for each other, although the difference in age must have concerned Anne. The young playwright certainly had the freedom for romantic liaisons in London. Shakespeare may have alluded to his marriage and feelings for Anne when he wrote in A Midsummer Night's Dream, “The course of true love never did run smooth; / But either it was different in blood … / Or else misgraffed in respect of years —”