Apollo had a love affair with Coronis, whom Artemis killed for marrying a mortal man. Coronis's son by Apollo was Asclepius, who became a god of healing and medicine.

Chione was visited by both Hermes and Apollo in the same night. She had a son from each union. With Apollo, she had Philammon, who became a great musician.

Cyrene was watching her father's flocks when a lion attacked. She wrestled the lion; Apollo saw this act of courage and fell in love. Together they produced two sons: Aristaeus and Idmon. Aristaeus was the inventor of bookkeeping, and Idmon became a famous prophet.

Apollo had a tryst with Hecuba, the wife of King Priam. Their love affair produced a son, Troilus. A prophecy predicted that Troy would never fall if Troilus lived to the age of twenty, but he was killed by Achilles during the Trojan War.

Manto, daughter of the seer Tiresias, was given to Apollo as a war prize. She perfected her prophetic abilities at Delphi and gave Apollo a son, Mopsus, who grew up to become a famous prophet as well.

Apollo's lover Phthia bore him three sons: Dorus, Laodocus, and Polypoetes. All three were killed by Aetolus to gain control of the country they ruled, which then became known as Aetolia.

When Rhoeo's father discovered she was pregnant, he assumed that her lover was mortal and punished her by putting her in a chest and setting her adrift in the ocean. But the child was Apollo's, and she landed safely on Delos, Apollo's own birthplace and an island sacred to him. There, she gave birth to Anius, a prophet who became one of Apollo's priests.

Apollo was closely associated with the arts, so it's no surprise that one of his lovers was a Muse; Thalia, who ruled comedy and idyllic poetry. Their children were the Corybantes, male followers of the nature goddess Cybele.

Another Muse, Urania, also had an affair with Apollo. Urania was the Muse of astrology and astronomy, and her union with Apollo produced two sons: Linus and Orpheus. Both grew up to be famous musicians.