Think of the marriage vow: for better or for worse. That's the nature of all aspects to Pluto, but this is particularly true in the case of oppositions.

Pluto Opposed North Node, Conjunct South Node. This aspect is all about the Western view of karma. Old debts need to be repaid before you can progress or evolve through the area indicated by the house placement of the North Node. On some level, you'll recognize the debts when they enter your life, and circumstances will force you to deal with them one way or another.

Pluto Opposed Ascendant. As an opposition here, Pluto conjuncts the seventh-house cusp. Relationships and partnerships may not be entirely pleasant for you. Get rid of your need to dominate, keep your spiritual self uplifted, and the influence will be diminished considerably.

Pluto Opposed Midheaven, Conjunct IC. There are easier ways to evolve as a spiritual being. But one thing is certain with this aspect: Much of your inner life will wrestle with the issue of spiritual evolvement. You may have to overcome an early childhood that was the equivalent of living under Hitler. You may get sidetracked. One way or another, the events and conditions in your life bring you back to the bottom line: Get it right this time around or you'll be back to try again.